Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 10. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_717Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman pancreatic cancer cell lineBxPC-3NANAImmunoassay detection0.001 MOI130% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_718Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman pancreatic cancer cell lineMIAPaCa-2NANAImmunoassay detection0.001 MOI70% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_719Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman caucasian pancreatic adenocarcinomaCFPAC-1NANAImmunoassay detection0.001 MOI111% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_720Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman pancreas adenocarcinoma cell lineAsPC-1NANAImmunoassay detection0.001 MOI128% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_721Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman pancreatic cancer cell lineBxPC-3NANAImmunoassay detection0.001 MOI148% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_722Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman pancreatic cancer cell lineMIAPaCa-2NANAImmunoassay detection0.001 MOI90% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_723Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman caucasian pancreatic adenocarcinomaCFPAC-1NANAImmunoassay detection0.001 MOI130% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_724Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman pancreas adenocarcinoma cell lineAsPC-1NANAImmunoassay detection0.001 MOI165% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_725Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNANANANANANANANASCID-B17 female mice inoculated subcutaneously in the right flank with 100 μl of 5.0E+6 BxPC-3Luc cells1.0E+5 PFUNA %volume change is 170 as compared to control 340 after 23 daysIntratumoralNANANA27417501
OV_726Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNANANANANANANANASCID-B17 female mice inoculated subcutaneously in the right flank with 100 μl of 5.0E+6 BxPC-3Luc cells1.0E+5 PFUNA %volume change is 90 as compared to control 340 after 23 daysIntratumoralNANANA27417501